Police are appealing for public assistance to help locate missing woman Helen Doober.

The 44-year-old Greens-borough woman was last seen in Studley Rd, Heidelberg about 4.30pm on Friday, (July 24).

Police and Helen’s family have concerns for her welfare as her disappearance is out of character.

Helen is approximately 160cm tall with a medium build, brown straight hair and blue eyes.

She was last seen wearing black pants, black jumper and black shoes and she was carrying a satchel.

It is believed she is driving her 2014 grey Holden Cruze sedan bearing registration ZQX-157.

Anyone who sights Helen or her vehicle is urged to contact the Heidelberg Police Station on 9450 8000.